What are the results and complications of DBS?

The results vary by location and specific center. In highly specialized centers with high patient volume, a 45-70% improvement in Parkinson’s disease rating scale scores “off” medication, as a result of DBS. This represents a major improvement in mobility. At most high volume center, the risk of stroke is 1-3%, the risk of severe stroke with death or permanent major disability is 0.5%, and the risk of device infection that requires further surgery for device removal is 4-5%.